**Job Description**
A 3-year Ph.D. position is available at the Department of Biotechnology and Biomedicine, DTU, focusing on ligand-observed NMR analysis of carbohydrate-active enzymes. Supervised by Associate Professor Birgitte Zeuner, the project aims to investigate the molecular basis of enzyme-substrate interactions in regioselective carbohydrate synthesis catalyzed by glycoside hydrolases. This Alliance PhD, partially funded by DTU and Villum Fonden, involves collaboration with the Norwegian University of Science and Technology (NTNU) and co-supervision by Associate Professor Gaston Courtade. The Ph.D. candidate will primarily focus on NMR analyses to provide insights into enzyme-substrate interactions within a collaborative research team.
**Skills & Abilities**
• Strong background in analytical chemistry, biochemistry, enzyme technology, or similar.
• Documented knowledge and experience with carbohydrate-active enzymes (prioritized).
• Well organized, structured, and self-driven.
• Enjoy interacting and collaborating with colleagues.
• Documented practical experience with NMR analysis, preferably with ligand-observed methods for studying protein-ligand interactions.
• Knowledge of carbohydrate chemistry (i.e., carbohydrate structures and terminology).
• Experience in working with carbohydrate-active enzymes (advantage, but interest in learning is a requirement).
• Experience in chemical carbohydrate synthesis and/or recombinant protein expression (advantageous).
• Excellent communication skills in English (written and spoken).
**Qualifications**
Required Degree(s) in:
• A two-year master’s degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master’s degree.
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