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August 21, 2025

**Job Description**
The Department of Chemical Biology and Therapeutics is seeking a highly motivated and innovative synthetic organic chemist specialized in medicinal chemistry. The incumbent will be responsible for designing and synthesizing molecules and compound libraries using modern computation-driven and property-focused design principles. They will collaborate with biologists to interpret assay data and iteratively design and prioritize new compounds. Projects will focus on advancing cutting-edge drug discovery programs for childhood catastrophic diseases, developing unique chemical approaches (protein degraders, synthetic gene regulators, and/or functional effectors) to degrade or manipulate targets relevant to pediatric oncology, neurodegenerative disorders, and sickle cell disease.

**Skills & Abilities**
• Strong knowledge and experience in understanding and application of underlying principles related to the techniques being performed.
• Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred.
• Proven performance in earlier role/comparable role.

**Qualifications**
Required Degree(s) in:
• Relevant scientific area

**Experience**
Experience Required:
• 5+ years (BSc)
• 3+ years (MSc)
• No prior experience (Ph.D)
Other:
• Strong knowledge and experience in understanding and application of underlying principles related to the techniques being performed.
• Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred.
• Proven performance in earlier role/comparable role.

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Experience
Experience Required: • 5+ years (BSc) • 3+ years (MSc) • No prior experience (Ph.D) Other: • Strong knowledge and experience in understanding and application of underlying principles related to the techniques being performed. • Experience in R&D methods and processes in lab setting, and execution of research projects for the laboratory preferred. • Proven performance in earlier role/comparable role.
Work Level
Bachelor, Masters, Ph.D
Employment Type
Research Job, See Details
Salary
Annual Salary: $60,320 - $105,040 per year Benefits: Exceptional benefits
Details
See Details Brief location description: Campus-based
School / Department / Center / Lab
• Department of Chemical Biology and Therapeutics
Supervisor Email
See Details
St. Jude Children’s Research Hospital
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