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Postdoctoral Associate – Scientific Machine Learning for Multiscale Biological Systems

August 21, 2025

**Job Description**
This postdoctoral associate position at Duke University focuses on scientific machine learning (SciML) as part of an NIH-funded Center for Excellence in Multiscale Immune Systems Modeling. The role involves leveraging and developing new equation learning methods, such as Physics-Informed Neural Networks (PINNs) and Biologically Informed Neural Networks (BINNs), to derive interpretable and computationally efficient differential equation models from multi-cellular agent-based models (ABMs) of Epstein-Barr Virus (EBV) and HIV-1 infection dynamics. The associate will collaborate with experimentalists to utilize infection data and ABM simulations to identify key mechanistic drivers of viral persistence and immune response, developing biologically-constrained machine learning-based model discovery pipelines to derive interpretable surrogate models from simulated ABM data and spatial-omics data.

**Skills & Abilities**
• Proficiency with deep learning frameworks (e.g., PyTorch, TensorFlow, and JAX).
• Experience in PDE/ODE modeling and numerical methods.
• Strong interest in interpretable ML and mechanistic model discovery.

**Qualifications**
Required Degree(s) in:
• Applied Mathematics
• Computational Science
• Statistics
• Machine Learning
• Related quantitative field

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Work Level
Postdoc
Employment Type
Research Job, See Details
Details
See Details Location Requirement: Relocation required to Durham, North Carolina, USA Campus-based
School / Department / Center / Lab
• Department of Mathematics • Department of Biostatistics & Bioinformatics • NIH-funded Center for Excellence in Multiscale Immune Systems Modeling
Supervisor(s)
Dr. Kevin Flores Dr. Micah Luftig Dr. Cliburn Chan Dr. Jianfeng Lu Dr. Veronica Ciocanel Dr. John Hickey Dr. Jessica Conway Dr. Elliott SoRelle
Supervisor Email
See Details