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August 21, 2025

**Job Description**
This 3-year Ph.D. position, part of an Alliance Ph.D. funded by DTU and Villum Fonden, is available in the Enzymatic Synthesis Technology group at the Department of Biotechnology and Biomedicine, DTU. Supervised by Associate Professor Birgitte Zeuner and co-supervised by Associate Professor Gaston Courtade (NTNU), the project focuses on ligand-observed NMR analysis of carbohydrate-active enzymes to investigate the molecular basis of enzyme-substrate interactions in regioselective carbohydrate synthesis catalyzed by glycoside hydrolases, contributing to new sustainable bioprocessing applications. The successful candidate will join a project team and collaborate with other Ph.D. students and postdocs, with work primarily at DTU and including extended stays at NTNU.

**Skills & Abilities**
• Strong background in analytical chemistry, biochemistry, enzyme technology or similar
• Documented knowledge and experience with carbohydrate-active enzymes (prioritized)
• Well organized, structured, self-driven
• Enjoy interacting and collaborating with colleagues
• Documented practical experience with NMR analysis, preferably with ligand-observed methods for studying protein-ligand interactions
• Knowledge of carbohydrate chemistry (carbohydrate structures and terminology)
• Experience in working with carbohydrate-active enzymes (advantage, while interest in learning it is a requirement)
• Experience in chemical carbohydrate synthesis and/or recombinant protein expression (advantageous)
• Excellent communication skills in English (written and spoken)

**Qualifications**
Required Degree(s) in:
• Analytical Chemistry
• Biochemistry
• Enzyme Technology
• Related fields

**Experience**
Other:
• Documented knowledge and experience with carbohydrate-active enzymes is prioritized.
• Documented practical experience with NMR analysis, preferably with ligand-observed methods for studying protein-ligand interactions.
• Experience in working with carbohydrate-active enzymes is an advantage.
• Experience in chemical carbohydrate synthesis and/or recombinant protein expression are considered advantageous.

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Experience
Other: • Documented knowledge and experience with carbohydrate-active enzymes is prioritized. • Documented practical experience with NMR analysis, preferably with ligand-observed methods for studying protein-ligand interactions. • Experience in working with carbohydrate-active enzymes is an advantage. • Experience in chemical carbohydrate synthesis and/or recombinant protein expression are considered advantageous.
Work Level
Ph.D
Employment Type
Full-time, Scholarship
Salary
Position Classification: Based on the collective agreement with the Danish Confederation of Professional Associations.
Valid Until
September 21, 2025
Details
Full-time Duration: 3 years Remote Work: No Location Requirement: Extended stays at NTNU (Trondheim, Norway) required Campus-based
School / Department / Center / Lab
• Department of Biotechnology and Biomedicine • Enzymatic Synthesis Technology group • Section for Protein Chemistry and Enzyme Technology
Supervisor(s)
Birgitte Zeuner Gaston Courtade
Supervisor Email
birz@bio.dtu.dk
Technical University of Denmark / Norwegian University of Science and Technology
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