Research Associate

**Job Description**
The role focuses on a high-impact project within the Wanford Group at King’s College London, specializing in the pathogenesis of antibiotic-resistant bacterial infections. The successful candidate will investigate the bacterial pathogen Klebsiella pneumoniae (Kp), a major antibiotic-resistant pathogen, to define bacterial factors required for systemic dissemination and to characterize the regulation of capsule expression during the transition between host compartments. This involves using comparative genomics, molecular genetics, in vitro and in vivo infection models, and microscopy/flow cytometry to understand Kp’s virulence mechanisms.

**Skills & Abilities**
• Proven ability to design, implement and analyse experiments.
• Experience with eukaryotic cell culture systems.
• Experience with in vivo infection models.
• Capacity to work independently and as part of a collaborative team.
• Excellent verbal and written communication skills (documented by presentations at academic meetings and track record of publications).
• Excellent organisational skills, academic integrity, and rigor.
• Currently hold a home office license; PIL AB (Desirable).
• Advanced molecular microbiology skills, including DNA/RNA extraction, PCR/qRT-PCR, genetic manipulation of bacterial pathogens (plasmid construction, transformation, generation of deletion mutants) (Desirable).
• Experience in fluorescence microscopy and/or flow cytometry (Desirable).

**Qualifications**
Required Degree(s) in:
• Molecular Microbiology
• Cell Biology
• Immunology
• Other relevant subject

**Experience**
Other:
• Prior experience with bacterial pathogens.

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