Bioinformatics Research Assistant

**Job Description**
This role focuses on advancing dementia research at the UK Dementia Research Institute (UK DRI) at King’s College London, specifically within Dr Sarah Marzi’s group. The successful candidate will conduct bioinformatics research to understand the molecular mechanisms underlying neurodegeneration, with a particular emphasis on analysing long-read RNA sequencing data for transcript splicing analysis and epigenetic data analysis. The goal is to determine the role of epigenetic regulation in neurodegenerative diseases, including ALS, Parkinson’s, and Alzheimer’s, by identifying epigenetic links between non-coding genetic and environmental risk factors in dementia.

**Skills & Abilities**
• Demonstrable expertise in using High-Performance Computing (HPC) Unix/Linux environments and the SLURM workload manager
• Proven experience with Oxford Nanopore Technologies (ONT) long-read sequencing data analysis and differential splicing analysis
• Programming skills in R
• Knowledge of basic neuroscience, neurodegenerative diseases and ALS
• Ability to work with version control systems, i.e., Git and GitHub
• An interest in the mission and research of the UK Dementia Research Institute (Desirable)

**Qualifications**
Required Degree(s) in:
• Genomics
• Related discipline (MSc)

**Experience**
Other:
• Demonstrable expertise in using High-Performance Computing (HPC) Unix/Linux environments and the SLURM workload manager
• Proven experience with Oxford Nanopore Technologies (ONT) long-read sequencing data analysis and differential splicing analysis

Note: We’ve analyzed the actual job post using AI, for more details visit the original job post by clicking on “Apply Now”!