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August 28, 2025

**Job Description**
This PhD position focuses on developing and applying algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models within a collaborative research program. The project will investigate spatial growth patterns of metastases, their drivers, and the involvement of the tumor microenvironment. The candidate will use high-resolution spatial omics techniques to prioritize molecular factors driving immune cell states, followed by in vivo validation, and will be embedded in both experimental and computational teams.

**Skills & Abilities**
� Interest in linking digital pathology with mechanistic experimental biology.
� Programming experience in Python.
� Excellent communication skills.
� Fluency in English.
� Collaborative personality with attention for detail.
� Experience in imaging or spatial omics data analysis.
� Background in biomedicine and digital pathology.

**Qualifications**
Required Degree(s) in:
� Bioinformatics
� Biomedicine
� Bioengineering
� Biotechnology
� Related fields

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Work Level
Ph.D
Employment Type
Full-time, Scholarship
Salary
Annual Salary: Competitive salary Benefits: Full benefits
Details
Full-time Duration: 4 years Remote Work: No Location Requirement: Campus-based
School / Department / Center / Lab
� VIB-Center for Inflammation Research � Guilliams team � Saelens team � Saeys team
Supervisor(s)
Prof. Wouter Saelens Prof. Yvan Saeys Prof. Martin Guilliams
Supervisor Email
wouter.saelens@irc.vib-ugent.be yvan.saeys@irc.vib-ugent.be martin.guilliams@irc.vib-ugent.be
VIB-Center for Inflammation Research / VIB (Flanders Institute for Biotechnology)
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