**Job Description**
Two Ph.D. positions are available to unravel the molecular mechanisms of virus self-assembly, focusing on how RNA-containing viruses are built up at the nanoscale. The project utilizes advanced microscopy and nanomanipulation techniques to record the live construction of viruses, providing fundamental understanding of these disease agents and informing the development of more effective antivirals. One position is centered on High Speed-Atomic Force Microscopy (HS-AFM) to visualize viral self-assembly at the single protein level and scrutinize protein-protein and protein-nucleic acid interactions. The second position focuses on Single Molecule Optical Tweezers (SMOT) to study self-assembly via the compaction force of protein-RNA interactions.
**Skills & Abilities**
• Clear interest in collaborative interdisciplinary research
• Excellent grades
• Creativity, determination, and motivation
**Qualifications**
Required Degree(s) in:
• Physics or a related field (MSc)
**Experience**
Other:
• Experience in nanoscience and/or atomic force microscopy is a plus
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