PhD position in Developmental Biology

**Job Description**
This Ph.D. project focuses on understanding how mRNA translation is regulated in space and time during early development, a crucial process, especially in germ cells and early embryos where transcription is absent. The successful candidate will build upon and optimize single-cell ribosome profiling methods for C. elegans to generate a genome-wide overview of translational regulation throughout development. In parallel, the role involves uncovering mechanisms controlling localized and cell-type-specific translation, and how these adapt across developmental stages and within subcellular compartments, to determine cell fate and function.

**Skills & Abilities**
• Interest in gene expression and translation regulation in the context of development
• Motivated to develop and optimize cutting edge single cell ribosome profiling techniques
• Affinity with bioinformatics
• Strong interest in (or experience with) single-cell RNA-sequencing methods and bioinformatics
• Strong interest in performing in vivo studies in C. elegans
• Proficiency in academic English, both spoken and written

**Qualifications**
Required Degree(s) in:
• Biology (Master’s degree)
• Developmental Biology (Strong background)
• Cell Biology (Strong background)
• Molecular Biology (Strong background)

**Experience**
Other:
• If you are within a few months of completing your MSc degree, we also welcome you to apply!

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