**Job Description**
This 7-month project, funded by The Medical Research Foundation, investigates the intersection of cancer biology and neuronal function, specifically how cancer and chemotherapy impact sensitisation and pain. The Post-Doctoral Research Associate/Fellow will join a multidisciplinary team in Nottingham to support a project titled “Extracellular vesicles as conduits for the transfer of biologically active compounds which mediate cancer chemotherapy based pain in early life.” The role involves laboratory-based research to identify and characterise cargo from extracellular vesicles (EVs) derived from chemotherapy-treated medulloblastoma cell lines, examining how these alter sensory neuron function, and determining their biodistribution and impact on pain behaviours in laboratory rodents. The project addresses chemotherapy-induced pain, a significant side-effect impacting patients and survivors, especially in childhood cancer, leading to long-term neurological and pain processing changes. This collaborative project involves expertise in childhood pain, molecular and cellular neuroscience, cancer biology, extracellular vesicle biology, and in vivo modelling, with the potential for rapid translation into patient benefit.
**Skills & Abilities**
• Enjoy teamwork
• Excellent communication skills
• Ability to work across different areas of the biomedical sciences
Note: We’ve analyzed the actual job post using AI, for more details visit the original job post by clicking on “Apply Now”!
