**Job Description**
This postdoctoral scholarship at Karolinska Institutet focuses on understanding the development and maintenance of epithelial tissues, and how alterations in progenitor cells and their environment contribute to disease. The project aims to characterize the functional relevance of progenitor-to-tumor cell niche transitions, specifically within the esophageal epithelium, by studying changes in local cell-cell networks during early esophageal epithelial transformation. This involves analyzing epithelial, stromal, and immune cell populations using mouse models, organoid co-cultures, and spatial sequencing technologies.
**Skills & Abilities**
• Curious, highly motivated, and creative.
• Strong background in cell or tissue biology.
• Practical experience working with mouse models.
• Experience analyzing sequencing data.
• Experience with organoid cultures and molecular biology (considered a strength).
• Excellent interpersonal and communication skills (in English, written and verbal).
• Personal suitability.
**Qualifications**
Required Degree(s) in:
• Doctorate (or a foreign degree deemed equivalent)
**Experience**
Other:
• Practical experience working with mouse models.
• Experience analyzing sequencing data.
• Experience with organoid cultures and molecular biology.
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