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September 10, 2025

**Job Description**
An ambitious researcher is sought to join a vibrant team at the Astbury Centre for Structural Molecular Biology. The project, funded for 3 years by the BBSRC, focuses on deciphering the myosin mechanochemical cycle through the development and application of time-resolved cryo-EM. This research aims to trap molecular motor myosin in various states to significantly advance understanding of its function, which is crucial for insights into diseases like early-onset cardiac disease and the modulation of function by small molecules. Exceptional facilities and training, including two Titan Krios electron microscopes, are available to support the project.

**Skills & Abilities**
• Experience in cryo-EM
• Experience in protein expression
• Experience in protein purification

**Qualifications**
Required Degree(s) in:
• Structural Biology
• Closely allied discipline
• PhD (or close to completion)

**Experience**
Other:
• Suitability for sponsorship under the Skilled Worker visa route (first-time applicants might need to qualify for salary concessions)
• Eligibility under the Global Talent visa for research and academic posts

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Experience
Other: • Suitability for sponsorship under the Skilled Worker visa route (first-time applicants might need to qualify for salary concessions) • Eligibility under the Global Talent visa for research and academic posts
Work Level
Postdoc
Employment Type
Research Job
Salary
Benefits: • 26 days holiday plus approximately 16 Bank Holidays/University closure days (42 days total) • Generous pension scheme plus life assurance (University contributes 14.5% of salary) • Discounted staff membership at The Edge (campus gym with pool, sauna, climbing wall, etc.) • Access to courses run by Organisational Development & Professional Learning team • Access to on-site childcare, shopping discounts, and travel schemes
Details
Full-time / Temporary Duration: 3 years Location Requirement: Campus-based in Leeds, UK
School / Department / Center / Lab
• Astbury Centre for Structural Molecular Biology
Supervisor(s)
Prof Stephen Muench Dr Charlie Scarff
Supervisor Email
s.p.muench@leeds.ac.uk c.a.scarff@leeds.ac.uk
University of Leeds
View profile
Industry
Education
Phone
+44 (0)113 243 1751 +44 (0)113 243 **** Show
Location
Leeds

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